The surname Ambrosio comes from the name Ambrosio, derived from the Latin Ambrosius, meaning Immortal.
It was originally found in Bologna in Emilia which was the capital of the province of Bologna.
Some variations of the surname are: Ambrosini, Ambrose, Ambrogio, Ambrosi, D'Ambrosio, Ambrogllio, Ambrosoni, bros, Brogetti, Ambros and more.

The name Ambrose quickly became popular because of devotion to St. Ambrose, who lived in the fourth century and was one of the founders of the Western Catholic Church.
St. Ambrose was governor of Liguria in northern Italy and became bishop of Milan in 374.