The origin of surname Ezquerra is the region of Aragon, Spain.

The name Ezquerra derives from the word "Left". This surname was originally a nickname derived from the physical characteristics of a reed of this lineage. The word is Basque-Celtic Izquierdo and results from the combination of the word "listen" which means "hand" and the word "Kerr" which means "left".

Some variations of this surname are: Esquerra, Ezquerra, Izquierda, Ezquerdo and others.